About 80 million years ago, mice and humans shared a common ancestor which makes the functions of their genes very similar. The coding regions of mice and humans can range from about 60% similar - 99% similar. These similarities allow researchers to study the causes, effects, details, and potential therapeutics of human disease.
The Center conducts research in many areas. While we rely heavily on zebrafish to pursue our research, there are many instances in which mice provide a better and more accurate model for studying human disease. Our mouse facility houses several uniquely modified genetic lines of mice to conduct research and our investigators have full access to the newly renovated 5,000 square feet mouse vivarium located two blocks away from our building. Both facilities fall under the purview of Duke’s Live Animal Research. All research conducted is in strict accordance with the appropriate regulations for animal care and use to ensure the appropriate treatment, housing and use of the animals.